Uncommon neurological dysfunction documented following COVID-19 vaccination

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In two separate articles within the Annals of Neurology, clinicians in India and England report circumstances of a uncommon neurological dysfunction referred to as Guillain-Barré syndrome after people have been vaccinated towards COVID-19.

Each reviews describe an uncommon variant of Guillain-Barré syndrome characterised by outstanding facial weak spot. Seven circumstances have been reported from a regional medical heart in Kerala, India, the place roughly 1.2 million individuals have been vaccinated with the AstraZeneca COVID-19 vaccine. 4 circumstances have been reported from Nottingham, England, in an space by which roughly 700,000 individuals obtained the identical vaccine. All eleven circumstances have been amongst individuals who had obtained that vaccine between 10 and 22 days earlier.

The frequency of Guillain-Barré syndrome in these areas was estimated to be as much as 10 occasions better than anticipated.

“If the hyperlink is causal it might be resulting from a cross-reactive immune response to the SARS-CoV-2 spike protein and parts of the peripheral immune system,” wrote the authors of the report from England.

The authors of each articles stress that clinicians must be vigilant in in search of this uncommon neurological syndrome following administration of COVID-19 vaccines.

No proof COVID vaccines can set off Guillain-Barré syndrome

Extra info:
Boby Varkey Maramattom et al, Guillain‐Barré syndrome following ChAdOx1‐S / nCoV ‐19 vaccine, Annals of Neurology (2021). DOI: 10.1002/ana.26143

Christopher Martin Allen et al, Guillain‐Barré syndrome variant occurring after SARS‐CoV ‐2 vaccination, Annals of Neurology (2021). DOI: 10.1002/ana.26144

Uncommon neurological dysfunction documented following COVID-19 vaccination (2021, June 21)
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